The second round matches of the WTA 1000 clay court tournament in Rome were played on Thursday, May 8.
- Marie Bouzkova (Czech Republic) – Beatriz Haddad Maia (Brazil, 18) – 6/0, 6/3
- Danielle Collins (USA, 29) – Elena-Gabriela Ruse (Romania, Q) – 6/3, 6/3
- Elise Mertens (Belgium, 25) – Suzan Lamens (Netherlands) – 3/6, 6/2, 6/3
- Jaqueline Cristian (Romania) – Yulia Putintseva (Kazakhstan, 23) – 7/6(2), 7/5
- Lucia Bronzetti (Italy) – Laura Siegemund (Germany) – 6/2, 6/2
Madison Keys also defeated Varvara Gracheva in her second-round match at the Rome tournament.
